Foundational Pathobiological and Novel Therapeutic Advances in Non-Cystic Fibrosis Bronchiectasis (NCFBE)
Emerging Investigational Evidence for Neutrophil-Directed Oral Therapies Based on DPP-1 Inhibition to Reduce Frequency of Exacerbations
Method of Physician Participation Utilized in Learning Process
There are no fees for participating and receiving CME credit for this activity. During the period February 8, 2022 through February 8, 2024, participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity, and are expected to view activity, totaling 1.0 hours, to successfully complete the activity and earn CME credit; 3) register and complete the evaluation form and post-test; 4) score 100% on the post-test; and 5) print out CME certificate.
Estimated Time to Complete Educational Activity
1.0 hours. Physicians must study the enduring activity, and are expected to view every segment to successfully complete the activity and earn CME credit.
In this web-based program, physicians will learn about recent developments in the management of bronchiectasis.
February 8, 2022
February 8, 2024
This complimentary CME educational activity is designed for all healthcare providers (HCPs) involved in developing, delivering, consulting, and monitoring care for patients with bronchiectasis, including pulmonologists, primary care physicians, respiratory medicine specialists, infectious disease specialists, and related clinicians.
Participation in this activity is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.
This activity is supported by an independent medical education grant from Insmed.
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Massachusetts Chan Medical School and CMEducation Resources, LLC. The University of Massachusetts Chan Medical School is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation Statement
The University of Massachusetts Chan Medical School, Office of Continuing Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Policy on Faculty & Provider Disclosure
It is the policy of the University of Massachusetts Chan Medical School to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the University of Massachusetts Chan Medical School are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.
Program Faculty and Disclosure
Prof. Francesco Blasi, MD, FERS
Professor of Respiratory Medicine
Department of Pathophysiology and Transplantation,
Università degli Studi di Milano
Member of Board of Directors, Università degli Studi di Milano.
Head Internal Medicine Department, Respiratory Unit and Adult Cystic Fibrosis Center
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano
Grants, Speaker Fees and Conferences: AstrraZeneca, Chiesi, Gilead, GSK, Grifols, Guidotti-Malesci, Insmed, Menari, Novartis, Pfizer, Sanofi, Viatris, Vertex and Zambon
Consulting: AstraZeneca, Chiesi, GSK, Manri
Program Managers and Web Editor Disclosure
Program Managers Gideon Bosker, MD and Denise Leary have nothing to disclose.
Upon completion of this activity, participants will be able to:
- Outline the epidemiology, unmet therapeutic needs, global demographics, and disease burden for NCFBE based on regional and global prevalence, susceptible populations, and strategies for early confirmation of the diagnosis of NCFBE
- Detail the global and local burden of NCFBE for patients and the healthcare system, especially in global regions—U.S., Europe, and Japan—with high disease burden and suboptimal recognition and delayed diagnosis of this challenging and widespread condition with high morbidity, poor treatment options, and significant mortality
- List the risk factors, early clinical clues, and clinical presentation of NCFBE in a wide range of patient with predisposing risk factors
- Apply International Guidelines—ERS, ATS, ARA, BTS, etc.—for managing NCFBE lung disease, even in the face of no officially approved therapies for this condition
- Implement patient-centric, self-care measures that ensure recognition of disease exacerbation and that improve regimen adherence and completion of treatments deployed for NCBE
- Detail the underlying pathobiology of NCFBE, especially the role of neutrophils as cellular triggers and maintenance of pathoinflammatory changes and pathways that are responsible for progressive lung tissue destruction and that predispose to recurrent exacerbations of NCFBE.
Hardware and Software Requirements:
To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to print out the CME certificate.
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